- Localized areas subcu swelling
- Response to a precipitant, including: meds, in particular ACE-I
- Can occur soon after initiation or later;
- Typically no urticara or itching
- Can be severe and life threatening due to airway issues
- Can occur w/anaphylactic rxns→ low bp w/systemic sx
- Swelling of face/head/larynx/tongue